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Zyvox
Generic Name:
linezolid (lin EZ oh lid)
Brand Names:
Zyvox
What is Zyvox?
Zyvox is an antibiotic that fights bacteria in the body. Zyvox is used to treat different types of bacterial infections, such pneumonia, skin infections, and infections that are resistant to other antibiotics. Zyvox may also be used for purposes other than those listed in this medication guide.
Before using Zyvox
Do not use Zyvox if you have used an MAO inhibitor such as isocarboxazid (Marplan), phenelzine (Nardil), rasagiline (Azilect), selegiline (Eldepryl, Emsam), or tranylcypromine (Parnate) within the past 14 days. Serious, life-threatening side effects can occur if you use Zyvox before the MAO inhibitor has cleared from your body. You also should not use Zyvox if you are also using any of these drugs: buspirone (BuSpar); meperidine (Demerol); a diet pill that contains a stimulant; cold or allergy medicines that contain a decongestant such as pseudoephedrine; ADHD medication such as Adderall or Dexedrine; migraine or cluster headache medication such as almotriptan (Axert), frovatriptan (Frova), naratriptan (Amerge), rizatriptan (Maxalt), sumatriptan (Imitrex), or zolmitriptan (Zomig); medication to treat Parkinson's disease or restless leg syndrome, such as carbidopa or levodopa (Lodosyn, Parcopa, Sinemet), pramipexole (Mirapex), or ropinorole (Requip); or an antidepressant such as amitriptyline (Elavil, Etrafon), citalopram (Celexa), doxepin (Sinequan), escitalopram (Lexapro), fluoxetine (Prozac, Sarafem, Symbyax), fluvoxamine (Luvox), imipramine (Janimine, Tofranil), paroxetine (Paxil), or sertraline (Zoloft), and others. You should not use Zyvox if you are allergic to linezolid, or if you have: untreated or uncontrolled high blood pressure; a carcinoid tumor; pheochromocytoma (adrenal gland tumor); or a severe thyroid disorder. If you have certain conditions, you may need a dose adjustment or special tests to safely use this medication. Before using Zyvox, tell your doctor if you have: high blood pressure; epilepsy or other seizure disorder; a thyroid disorder; kidney or liver disease; or bone marrow suppression or a weak immune system. Some people have developed a life-threatening condition called lactic acidosis while taking Zyvox. You may be more likely to develop lactic acidosis if you have liver or kidney disease, congestive heart failure, or if you drink large amounts of alcohol. Talk with your doctor about your individual risk. You may be more likely to develop lactic acidosis if you have liver disease, kidney disease, or congestive heart failure, or if you drink large amounts of alcohol. Talk with your doctor about your individual risk. FDA pregnancy category C. It is not known whether Zyvox is harmful to an unborn baby. Tell your doctor if you are pregnant or plan to become pregnant during treatment. It is not known whether linezolid passes into breast milk or if it could harm a nursing baby. Do not use this medication without telling your doctor if you are breast-feeding a baby.
Zyvox side effects
Get emergency medical help if you have any of these signs of an allergic reaction: hives; difficulty breathing; swelling of your face, lips, tongue, or throat. Call your doctor at once if you have a serious side effect such as: pale skin, easy bruising or bleeding, unusual weakness; fever, chills, body aches, flu symptoms; diarrhea that is watery or bloody; blurred vision, trouble seeing colors numbness, burning, pain, or tingly feeling in your hands or feet; seizure (convulsions); or lactic acidosis - muscle pain or weakness, numb or cold feeling in your arms and legs, trouble breathing, stomach pain, nausea with vomiting, slow or uneven heart rate, dizziness, or feeling very weak or tired. Less serious Zyvox side effects may include: headache, dizziness; nausea, vomiting, constipation, stomach pain or upset; sleep problems (insomnia); mild rash or itching; discolored tongue, unusual or unpleasant taste in the mouth; vaginal itching or discharge; or yeast infection in the mouth. This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.
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