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Trental
Generic Name:
pentoxifylline (pen tox I fi leen)
Brand Names:
Pentoxil, Trental
What is Trental (pentoxifylline)?
Pentoxifylline changes the shape of red blood cells in your blood. This makes it easier for these blood cells to fit into small arteries (blood vessels). Pentoxifylline is used to improve blood flow. Improved blood flow helps to reduce leg cramps and other symptoms of vascular disease (disease related to veins and arteries). Pentoxifylline may also be used for purposes other than those listed in this medication guide.
How should I take Trental (pentoxifylline)?
Take pentoxifylline exactly as directed by your doctor. If you do not understand these instructions, ask your pharmacist, nurse, or doctor to explain them to you. Take each dose with a full glass (8 ounces) of water. Take pentoxifylline with food or an antacid to lessen stomach upset. Pentoxifylline is usually taken three times a day. Follow your doctor's instructions. If you experience side effects, talk to your doctor. You may only need to take pentoxifylline twice a day. Do not break, crush, or chew the tablets. Swallow them whole. They are specially coated to protect your stomach. Do not stop taking this medication suddenly. It may take up to 8 weeks for you to see the beneficial effects of pentoxifylline, although you may begin to feel better as soon as 2 weeks after starting therapy. Store pentoxifylline at room temperature away from moisture and heat.
Trental (pentoxifylline) side effects
If you experience any of the following serious side effects, stop taking pentoxifylline and seek medical attention: an allergic reaction (difficulty breathing; closing of your throat; swelling of your lips, tongue, or face; or hives); chest pain or an irregular heartbeat; severe dizziness, headache, nosebleeds, or blurred vision; nausea or vomiting; or swollen feet or ankles. Other, less serious side effects may be more likely to occur. Continue to take pentoxifylline and talk to your doctor if you experience insomnia, red eyes, or nervousness. This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.
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