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Reglan
Generic Name:
metoclopramide (MET oh KLOE pra mide)
Brand Names:
Metozolv ODT, Reglan
What is Reglan?
Reglan increases muscle contractions in the upper digestive tract. This speeds up the rate at which the stomach empties into the intestines. Reglan is used short-term to treat heartburn caused by gastroesophageal reflux in people who have used other medications without relief of symptoms. It is also used to treat nausea and vomiting. Reglan is also used to treat slow gastric emptying in people with diabetes (also called diabetic gastroparesis), which can cause nausea, vomiting, heartburn, loss of appetite, and a feeling of fullness after meals. Reglan may also be used for other purposes not listed in this medication guide.
Before taking Reglan
You should not take Reglan if you are allergic to metoclopramide, or if you have: bleeding or blockage in your stomach or intestines; a perforation (hole) in your stomach or intestines; epilepsy or other seizure disorder; or an adrenal gland tumor (pheochromocytoma). If you have any of these other conditions, you may need a dose adjustment or special tests to safely take Reglan: kidney disease; liver disease (especially cirrhosis); congestive heart failure; high blood pressure; Parkinson's disease; diabetes (your insulin dose may need adjusting); or a history of depression. FDA pregnancy category B. Reglan is not expected to be harmful to an unborn baby. Tell your doctor if you are pregnant or plan to become pregnant during treatment. Metoclopramide can pass into breast milk and may harm a nursing baby. Do not use Reglan without telling your doctor if you are breast-feeding a baby.
Reglan side effects
Get emergency medical help if you have any of these signs of an allergic reaction to Reglan: hives; difficulty breathing; swelling of your face, lips, tongue, or throat. Stop using Reglan and call your doctor at once if you have any of these serious side effects: tremors, or restless muscle movements in your eyes, tongue, jaw, or neck; mask-like appearance of the face; very stiff (rigid) muscles, high fever, sweating, confusion, fast or uneven heartbeats, tremors, feeling like you might pass out; depressed mood, thoughts of suicide or hurting yourself; hallucinations, anxiety, agitation, jittery feeling, trouble staying still; swelling, fluid retention; jaundice (yellowing of your skin or eyes); or seizure (convulsions). Less serious Reglan side effects may include: feeling restless, drowsy, tired, or dizzy; headache, sleep problems (insomnia); nausea, vomiting, diarrhea; breast tenderness or swelling; changes in your menstrual periods; or urinating more than usual. This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.
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