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Cafergot
Generic Name:
caffeine and ergotamine (oral/rectal) (KAF een and er GOT a meen)
Brand Names:
Cafergot, Migergot
What is caffeine and ergotamine?
Caffeine is a stimulant that causes narrowing of blood vessels (vasoconstriction). Ergotamine is in a group of drugs called ergot alkaloids (ER-got AL-ka-loids). It works by narrowing the blood vessels around the brain. Ergotamine also affects blood flow patterns that are associated with certain types of headaches. The combination of caffeine and ergotamine is used to treat or prevent a migraine type headache. This medication will only treat a headache that has already begun. It will not prevent migraine headaches or reduce the number of attacks. Caffeine and ergotamine should not be used to treat common tension headaches or any headache that seems to be different from your usual migraine headaches. Caffeine and ergotamine may also be used for other purposes not listed in this medication guide.
How should I use caffeine and ergotamine?
Use this medication exactly as prescribed by your doctor. Never use more than your prescribed dose of caffeine and ergotamine. Follow the directions on your prescription label. Tell your doctor if the medicine seems to stop working as well in treating your migraine attacks. Caffeine and ergotamine is not for daily use. To use caffeine and ergotamine tablets: Take 2 tablets of caffeine and ergotamine as soon as you notice headache symptoms, or after an attack has already begun. If your headache does not completely go away, you may take 1 more tablet after at least 30 minutes have passed. If additional medication is needed, you may take 1 tablet every 30 minutes up to a total of 6 tablets for one migraine attack. If you still have migraine symptoms after taking a total of 6 tablets, call your doctor. Do not take more than a total of 6 tablets in any 24-hour period. Do not take more than a total of 10 tablets over a period of 7 days. To use caffeine and ergotamine rectal suppositories: Insert 1 suppository at the first sign of migraine headache symptoms, or after an attack has already begun. If your headache does not completely go away, use 1 more suppository after at least 1 hour has passed. Do not take a rectal suppository by mouth. It is for use only in your rectum. Try to empty your bladder just before using the suppository. Remove the outer wrapper from the suppository and insert it gently into the rectum, pointed tip first. Avoid handling the suppository too long or it will melt in your hands. For best results, lie down after inserting the suppository and hold it in for a few minutes. The suppository will melt quickly once inserted and you should feel little or no discomfort while holding it in. Avoid using the bathroom just after you have inserted the suppository. If you still have migraine symptoms after using a total of 2 rectal suppositories, call your doctor. Do not use more than a total of 2 suppositories per headache. Do not use more than a total of 5 suppositories over a period of 7 days. Do not give this medication to anyone else, even if they have the same headache symptoms you have. Caffeine and ergotamine can be dangerous if it is used to treat headache in a person who has not been diagnosed by a doctor as having true migraine headaches. Store caffeine and ergotamine at room temperature away from moisture, heat, and light. Do not use any stored caffeine and ergotamine if the expiration date on the label has passed.
Caffeine and ergotamine side effects
Get emergency medical help if you have any of these signs of an allergic reaction: hives; difficulty breathing; swelling of your face, lips, tongue, or throat. Stop using caffeine and ergotamine and call your doctor at once if you have a serious side effect such as: sudden numbness or weakness, especially on one side of the body; sudden headache, confusion, problems with vision, speech, or balance; fast or slow heart rate; muscle pain in your arms or legs; leg weakness; numbness or tingling and a pale or blue-colored appearance in your fingers or toes; severe pain in your stomach or lower back; urinating less than usual or not at all; painful sores on your rectum after using the rectal suppositories; swelling or itching in any part of your body; cough with stabbing chest pain and trouble breathing; or dangerously high blood pressure (severe headache, blurred vision, buzzing in your ears, anxiety, confusion, chest pain, shortness of breath, uneven heartbeats, seizure). Less serious side effects may include: dizziness, spinning sensation; weakness; nausea, vomiting; or mild itching. This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.
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